Osteoporosis is caused by losing bone density, which leads to bone fragility and an increased risk of fractures of the hip, spine, and wrist.
Bone is a living tissue, which is constantly being absorbed and replaced. Osteoporosis occurs when the rate of removal of old bone exceeds the formation of new bone.
There are people who are at a higher risk than others for developing osteoporosis.
Risk factors for osteoporosis and osteoporotic fractures are listed below:
- Genetics:
Family history —having a parent or close relative with osteoporosis
- Family history of osteoporotic fractures
- Small body frames
- Low BMI < 19
- Lifestyle:
- Tobacco use
- Excessive alcohol consumption
- Sedentary lifestyle
- Dietary:
- Low calcium intake
- Vitamin D deficiency
- Bariatric surgery
- Malabsorption syndromes such as celiac disease and inflammatory bowel disease
- Eating disorders
- Hormonal causes:
- Hyperparathyroidism: increased activity of the parathyroid glands
- Hyperthyroidism: an excessive secretion of the thyroid glands
- Cushing’s disease
- Increased prolactin secretion
- Hypogonadism
– Women: menopause
– Men: low testosterone and estradiol secretion
– Men: prostate cancer
- Medication:
- Long-term use of high-dose corticosteroid treatment
- Overdose of levothyroxine sodium — for hypothyroidism
- Long term use of warfarin — an anticoagulant
- Long term use of heparin — an anticoagulant
- Diuretics for blood pressure
- SSRIs for depression
- PPIs for reduction of gastric acid
- Anti-epileptics
- Thiazolidinediones for diabetes
- Immunosuppressive medications
- Lithium (used to treat bipolar disorder)
- Other medical conditions:
- Kidney failure
- Malabsorption syndromes
- Bariatric surgery
- Chronic obstructive pulmonary disease
- Rheumatoid arthritis
- Chronic liver disease
- Systemic mastocytosis
- Spine injury
- Hypercalciuria
- Organ transplantation
- HIV
- Genetics syndromes:
- Osteogenesis imperfecta
- Marfan syndrome
- Ehlers-Danlos syndrome
- Homocystinuria
- Cancer:
- Thyroid
- Multiple myeloma
- Leukemia
- Lymphoma
- Lung
- Ovarian
If you have one or more risk factors for osteoporosis, it is important to consult with your physician. In order to prevent osteoporosis, it is recommended to add a calcium supplement to your daily diet. DENSITY™ is a new generation of calcium with doubled absorption.
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